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A New Reality for Many Women on Weight Loss Medications
For the past few years, compounded weight loss medications (like semaglutide and tirzepatide) have offered hope to thousands of women struggling with weight loss. These affordable alternatives gave access to weight loss treatments without the sky-high costs of brand-name versions.
But change is here and it’s causing worry. Due to evolving FDA regulations and tighter enforcement on compounding pharmacies, many patients are finding that compounded GLP-1 weight loss medications may soon be no longer available.
So, what happens now? If you’re one of the many women 40+ who have benefited from compounded GLP-1 medications, don’t panic — but do prepare.
Here’s what you need to know, and how Ample Health & Wellness can help guide you through this transition with grace and confidence.
Why Were Compounded GLP-1 Weight Loss Medications So Popular?
As the demand for weight loss medications surged, many found that name-brand medications (such as Ozempic®, Wegovy®, and Mounjaro®) were either too expensive, difficult to find, or not covered by insurance for weight loss purposes.
Compounded versions became a solution. These were often:
- More affordable
- Easier to access
- Available through weight loss clinics and online pharmacies
However, compounded medications are not FDA-approved, and concerns about quality control, consistency, and safety have led to increased scrutiny. As a result, the FDA is limiting access and many pharmacies have stopped or will stop offering these medications.
What Does This Mean for You?
Losing access to compounded GLP-1 medications may feel discouraging, especially if they were helping you achieve weight loss success. You may now face:
- Higher costs for name-brand medications
- Potential insurance barriers
- Fear of regaining weight if stopping the medication
This shift is unsettling, but it’s also a wake-up call: weight loss medications alone should never be the only strategy. This is your opportunity to refocus on holistic, sustainable lifestyle changes that support your health — with or without medication.
What to Do Next: Steps for Transitioning
If compounded GLP-1 medications are no longer an option, here’s what you can do:
1. Talk to Your Healthcare Provider
- Review if switching to a name-brand GLP-1 is appropriate.
- Explore other medication options that may support weight loss or appetite regulation.
2. Explore Insurance Options
- Ask about prescription assistance programs.
- Look into savings cards and prior authorization routes.
3. Prioritize Lifestyle Changes
- Recommit to a balanced, nutrient-dense diet.
- Establish consistent movement and exercise routines.
- Focus on sleep, hydration, and stress management.
4. Seek Holistic Coaching and Support
- This is where Ample Health & Wellness can make the biggest difference right now.
Why Holistic Support Matters More Than Ever
While GLP-1 medications can suppress appetite and support weight loss, they do not teach sustainable habits. When medications are reduced or stopped, those old habits can return unless they’ve been replaced with healthier ones.
At Ample Health & Wellness, we specialize in helping women over 40:
- Build healthy, mindful eating patterns
- Develop stress-reducing and mindset-shifting habits
- Stay accountable and supported through every phase of the journey
- Prepare for life after medications with confidence
Whether you are transitioning off compounded medications or looking for support while on a brand-name GLP-1, our holistic programs are designed to fill the gap and help you thrive.
Remember: your success does not depend on a shot. It depends on what you do, day after day, with the guidance of a coach and the support of a wellness community.
Final Ample Thoughts
Yes, the end of compounded GLP-1 weight loss medications may feel overwhelming. But this does not have to be the end of your weight loss journey. In fact, it can be the beginning of a new chapter …one where you focus on habits, mindset, and holistic wellness that carry you through for life.
At Ample Health & Wellness, we’re here to walk with you through this transition and beyond.
👉🏾Contact us today to learn more about our personalized holistic weight loss coaching and start building your sustainable weight loss strategy — medication or not.

About the Author: Dr. Kisha Pickford, DNP, is a board-certified nurse practitioner and holistic nutrition weight loss coach at Ample Health & Wellness. She helps women over 40 achieve sustainable weight loss and whole-body wellness through holistic, evidence-based coaching.
📚 References
FDA. (2024). Compounded drugs. U.S. Food and Drug Administration. https://www.fda.gov/drugs/human-drug-compounding/compounded-drugs
Rubino, D., et al. (2021). New medications for obesity treatment: GLP-1 receptor agonists. Nature Reviews Endocrinology, 17(4), 240–250. https://doi.org/10.1038/s41574-021-00452-3
Cleveland Clinic. (2023). GLP-1 agonists for weight loss. https://my.clevelandclinic.org/health/treatments/24486-glp-1-agonists-for-weight-loss
